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Fig. 4 | Respiratory Research

Fig. 4

From: Oxidative stress and Nrf2 expression in peripheral blood mononuclear cells derived from COPD patients: an observational longitudinal study

Fig. 4

Nrf2/ARE mRNA expression in PBMCs derived from both groups at baseline and at follow-up. mRNA was analyzed by quantitative real-time PCR; normalized gene expression levels are given as the ratio between the mean value for the target gene and β-actin in each sample. Data are expressed as mean ± SD; *p < 0.01 versus no-COPD. **p < 0.01 vs baseline. Abbreviations: GCLC, glutamate-cysteine ligase catalytic; HO-1, heme oxygenase-1; mRNA, messenger RNA; Nrf2, nuclear factor-E2-related factor 2; PBMCs, peripheral blood mononuclear cells; PCR, polymerase chain reaction. a Nrf2 mRNA expression. b HO-1 mRNA expression. c GCLC mRNA expression

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