Airway regulatory T cells are decreased in COPD with a rapid decline in lung function

Respiratory Research

Table 1 Basic characteristics of COPD subjects, by rate of decline in lung function

	COPD rapid decline in LF n = 12	COPD non-rapid decline in LF n = 10
Female:Male	2:10	4:6
Age^b	63 ± 7	67 ± 6
BMI^a	26 ± 3	25 ± 3
Current:Ex-smokers^a	8:4	3:7
Pack-years^a	37.5 ± 16	33 ± 11
FEV₁, percent of predicted^b	60 ± 15	63 ± 19
FEV₁/VC^b	0.52 ± 0.12	0.54 ± 0.11
BAL-recovery, %^c	44 ± 16	40 ± 19
Annual decline in FEV₁, ml^b	86 ± 29	16 ± 17
Use of inhaled corticosteroids; Yes:No^c	2:10	5:5

Values given as mean ± SD unless indicated differently. Statistical comparisons between the two groups were made using the Mann–Whitney U-test and a p-value < 0.05 was considered significant
NS Not significant, Pack-years (number of cigarettes smoked per day/20) × number of years smoked, FEV₁ forced expiratory volume in 1 s, VC vital capacity
^aAt time of identification in the OLIN COPD study
^bAt time of inclusion in the current study
^cAt time of bronchoscopy in the current study

ISSN: 1465-993X