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Table 4 Characteristics of five mechanical ventilation phenotypes in the validation cohort

From: Five novel clinical phenotypes for critically ill patients with mechanical ventilation in intensive care units: a retrospective and multi database study

Features (mean ± sd, missing ratio)

Profile I (n = 542)

Profile II (n = 124)

Profile III (n = 52)

Profile IV (n = 81)

Profile V (n = 205)

P value

Age (years)

66.58 ± 11.37

58.54 ± 15.44

59.37 ± 17.11

55.2 ± 17.49

40.17 ± 10.98

9.39E−102

T (℃)

36.83 ± 0.49

37.16 ± 0.64

37 ± 0.49

37.01 ± 0.98

37.19 ± 0.48

4.9527E−13

APACHE2

14.11 ± 4.94

23.5 ± 7.21

14.79 ± 4.64

22.4 ± 10.97

11.54 ± 4.96

0.11487362

SOFA

5.85 ± 2.6

11.84 ± 2.84

6.14 ± 2.93

9.85 ± 4.5

5.37 ± 2.72

0.6420805

RR (insp/min)

15.53 ± 2.57

17.08 ± 2.58

16.04 ± 2.1

20.14 ± 5.07

15.62 ± 1.89

4.4237E−22

FiO2 (%)

36.79 ± 5.47

43.97 ± 7.43

41.13 ± 4.93

51.02 ± 17.19

36.37 ± 5.76

0.00019347

SpO2 (%)

98.99 ± 1.14

98.26 ± 1.41

99.19 ± 1.12

96.16 ± 5.98

99.39 ± 0.87

0.21325563

Pmean (cmH2O)

8.26 ± 1.11

10.73 ± 1.91

9.19 ± 1.52

11.86 ± 3.76

8.16 ± 1.1

0.00017063

Ppeak (cmH2O)

17.29 ± 3.41

20.92 ± 3.42

19.25 ± 3

21.91 ± 6.08

16.75 ± 3.16

0.17203648

PEEP (cmH2O)

5.74 ± 1.5

8.14 ± 3.04

17.42 ± 2.89

10.21 ± 6.78

5.9 ± 1.56

8.4678E−08

VT (mL/B)

420.85 ± 63.81

436.2 ± 69.98

419.73 ± 68.94

423.27 ± 104.77

421.87 ± 65.94

0.92926968

PO2 (mmHg)

130.76 ± 32.35

113.85 ± 35.64

138 ± 27.8

130.62 ± 59.47

157.53 ± 35.2

7.0463E−16

PCO2 (mmHg)

38.2 ± 4.32

40.21 ± 5.02

38.04 ± 4.97

43.06 ± 10.13

37.61 ± 4.08

0.31930209

HR (BPM)

81.53 ± 12.37

100.91 ± 14.87

86.54 ± 15.16

97.48 ± 22.85

99.1 ± 11.71

0.53986379

MAP (mmHg)

88.51 ± 10.08

90.02 ± 8.93

89.15 ± 10.57

87.25 ± 19.48

91.58 ± 11.32

0.01042881

CVP (mmHg)

7.55 ± 1.26

10.07 ± 2.21

8.18 ± 1.28

9.46 ± 2.87

7.61 ± 1.45

0.01687499

Pv-aCO2 (mmHg)

5.5 ± 1.55

5.29 ± 2.49

5.68 ± 1.58

5.44 ± 2.57

5.65 ± 1.78

0.37027728

Lac (mmol/L)

1.87 ± 1.03

2.63 ± 1.84

2 ± 1.24

4.11 ± 5.1

1.89 ± 1.1

0.0028773

P(v-a)CO2/C(a-v)O2 ratio

1.51 ± 0.88

1.52 ± 0.65

1.56 ± 1.13

1.54 ± 1.55

1.61 ± 0.62

0.20245812

PI

2.88 ± 1.27

1.64 ± 1.05

2.15 ± 1.02

2.47 ± 2.35

2.36 ± 1.19

4.9826E−06

Hb (g/dL)

110.55 ± 18.13

101.19 ± 17.9

103.25 ± 18.67

105.81 ± 22.91

104.63 ± 18.31

0.000066705

Balance (mL)

− 103.08 ± 995.45

− 1639.78 ± 3940.19

− 379.04 ± 1632.88

− 388.62 ± 2459.24

− 233.08 ± 1210.63

0.49045364

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Respiratory Research

ISSN: 1465-993X

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