Table 2 Clinical characteristics and biomarkers expression in ALI patients

Mean age ± SD (years)

57.2 ± 8.3

58.6 ± 8.5

57.1 ± 8.3

0.298

BMI (mean ± SD)

26.1 ± 2.4

26.3 ± 2.3

26.1 ± 2.4

0.719

Male

21 (46.6%)

15 (50.0%)

6 (40.0%)

0.391

Current smoker

30 (66.7%)

23 (76.3%)

7 (48.8%)

0.581

COPD

8 (17.7%)

6 (21.1%)

2 (10.6%)

0.058

Hypertension

13 (28.8%)

8 (28.9%)

5 (32.1%)

0.691

Chronic heart failure

5 (11.1%)

4 (13.2%)

1 (9.4%)

0.082

Diabetes

11 (24.4%)

8 (26.3%)

3 (23.3%)

0.689

Operation time: Mean ± SD (min)

182.1 ± 17.2

178.9 ± 13.6

N/A

N/A

Blood loss: Mean ± SD (ml)

280.2 ± 20.5

265.8 ± 21.4

N/A

N/A

ICU duration

7.2 ± 2.3

10.5 ± 2.6

N/A

N/A

Tracheal tube retaining time (days)

4.5 ± 1.6

5.8 ± 1.7

N/A

N/A

Relative MALAT1

1.8 ± 0.7

1.2 ± 0.7

2.5 ± 0.5

 < 0.01

Relative miR-181a-5p

1.9 ± 0.2

2.3 ± 0.9

0.5 ± 0.1

 < 0.01

Relative Fas

2.0 ± 0.4

1.3 ± 0.5

2.8 ± 1.2

 < 0.01

Relative TNF-α

1.7 ± 0.5

2.9 ± 0.8

1.1 ± 0.3

 < 0.01

Relative IL-1β

1.8 ± 0.6

2.2 ± 1.3

1.3 ± 0.8

 < 0.01

Relative IL-6

1.6 ± 0.2

2.9 ± 0.5

1.7 ± 0.6

 < 0.01