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Table 1 Clinical characteristics of 483 patients with acute PTE

From: Association between serum calcium and prognosis in patients with acute pulmonary embolism and the optimization of pulmonary embolism severity index

Characteristics

All patients (n = 483)

Patients with hypocalcemia (serum calcium level ≤ 2.13 mmol/L, n = 239)

Patients without hypocalcemia (serum calcium level > 2.13 mmol/L, n = 244)

P value

Age(years)

62 (51, 70)

62 (51, 72)

61.5 (51, 69)

0.660

Male sex

224 (46.38%)

109 (45.61%)

115 (47.13%)

0.737

Symptoms on admission

 Dyspnea

313 (64.80%)

154 (64.44%)

159 (65.16%)

0.867

 Chest pain

67 (13.87%)

28 (11.72%)

39 (15.98%)

0.175

 Hemoptysis

45 (9.32%)

22 (9.21%)

23 (9.43%)

0.933

 Syncope

53 (10.97%)

28 (11.72%)

25 (10.25%)

0.616

Comorbidities for PTE

 Chronic heart failure

138 (28.57%)

67 (28.03%)

71 (29.10%)

0.796

 Altered mental status

81 (16.77%)

47 (19.67%)

34 (13.93%)

0.092

 Sugery or trauma within 3 months

168 (36.05%)

89 (39.38%)

79 (32.92%)

0.146

 Immobilization state

181 (38.92%)

89 (39.38%)

92 (38.49%)

0.845

 Chronic pulmonary disease

140 (28.99%)

60 (25.10%)

80 (32.79%)

0.063

 Cancer

169 (34.99%)

88 (36.82%)

81 (33.20%)

0.404

 Previous history of DVT

295 (62.63%)

139 (60.43%)

156 (63.93%)

0.335

 Underwent CPR in hospital

26 (5.39%)

19 (7.95%)

7 (2.88%)

0.014

 Glucocorticoid therapy history

117 (25.05%)

65 (28.63%)

52 (21.67%)

0.082

 Hyperlipidemia or diabetes

177 (37.98%)

88 (38.43%)

89 (37.55%)

0.846

 Hypertension

198 (42.49%)

104 (46.02%)

94 (39.17%)

0.135

Physical examination findings

 Systolic blood pressure (mmHg)

122 (108, 135.25)

120 (104.75, 135)

123.5 (110, 136)

0.031

 Diastolic blood pressure (mmHg)

74 (64, 82)

72 (61, 81)

75 (66, 83)

0.036

 Pulse rate (b.p.m)

92 (80, 108)

94 (82, 110)

90 (78, 105)

0.012

 Respiratory rate (/min)

20 (18, 22)

20 (18, 23)

20 (18, 20)

 < 0.001

 Temperature ( °C)

36.7 (36.4, 37.1)

36.8 (36.5, 37.3)

36.6 (36.4, 37.0)

 < 0.001

 Shock index

0.756 (0.625, 0.916)

0.790 (0.634, 0.977)

0.721 (0.613, 0.876)

0.004

Admission laboratory markers

 White blood cell (× 109/L)

8.77 (6.29, 12.25)

8.98 (6.40, 12.60)

8.59 (5.99, 11.85)

0.260

 Neutrophil proportion (%)

75.30 (66.13, 85.38)

79.9 (71.05, 87.25)

72.25 (63.25, 80.58)

 < 0.001

 Hemoglobin (g/L)

119.0 (99.5, 135.0)

109 (91, 130.25)

127 (113, 142)

 < 0.001

 Platelet (× 109/L)

191 (138, 263)

179 (130, 241)

213 (150, 276)

 < 0.001

 D-dimer (mg/L)

4.98 (2.16, 11.45)

6.40 (3.33–16.40)

3.47(1.63–8.59)

 < 0.001

 ALT (U/L)

21 (14, 40)

20 (13, 47)

22 (14, 36)

0.858

 GGT

49 (29.5, 99)

79.5 (33.5, 142.75)

42 (25, 66)

0.012

 Albumin (g/L)

34 (30, 38)

30 (26, 34)

37 (34, 40)

 < 0.001

 Creatinine (umol/L)

69 (57, 85)

66 (54.75, 92.25)

70 (59, 82.5)

0.510

 CKMB (ug/L)

0.90 (0.50, 1.90)

1.05 (0.50–2.20)

0.80 (0.50–1.50)

0.005

 cTnI (ng/mL)

0.022 (0.009, 0.113)

0.030 (0.010, 0.181)

0.020 (0.006, 0.093)

0.046

 NT-proBNP (pg/mL)

553 (148.5, 2086.25)

707 (207, 2909)

393 (104,1445)

 < 0.001

 Serum potassium (mmol/L)

3.9 (3.6, 4.2)

3.8 (3.5, 4.2)

3.9 (3.7, 4.2)

0.031

 Serum sodium (mmol/L)

138 (136, 140)

138 (135, 140)

138 (136, 140)

0.213

 Serum chlorine (mmol/L)

103 (100, 106)

104 (99, 107)

103 (100, 105)

0.020

 Blood glucose

6.65 (5.50, 8.88)

7.25 (5.70, 9.80)

6.40 (5.30, 7.73)

 < 0.001

 PH

7.438 (7.405, 7.463)

7.440 (7.402, 7.471)

7.435 (7.407–7.457)

0.342

 SaO2 (%)

94.00 (89.53, 96.88)

93.90 (89.00, 97.00)

94.30 (90.00, 96.50)

0.557

Echocardiography

 sPAP(mmHg)

57 (44, 71.5)

56 (41, 67)

57 (45.5, 72)

0.188

 RVD

131 (29.91%)

59 (27.31%)

72 (32.43%)

0.282

PESI and sPESI

 PESI

99 (76, 127)

104 (79, 135)

98 (75, 119)

0.026

 sPESI

1 (1, 2)

1 (1, 2)

1 (1, 2)

0.101

  1. P values indicating statistically significant differences between patients with and without hypocalcemia are bolded
  2. Missing data: 0.21% for Syncope, 3.52% for Surgery or trauma within 3 months, 3.73% for Immobilization state, 2.48% for Previous history of DVT, 0.21% for Underwent CPR in hospital, 3.31% for Glucocorticoid therapy history, 3.52% for Hyperlipidemia or Diabetes, 3.52% for Hypertension, 5.18% for Systolic blood pressure (mmHg), 5.18% for Diastolic blood pressure (mmHg), 3.31% for Pulse rate (b.p.m), 0.21% for White Blood Cell (× 109/L), 0.62% for Neutrophil proportion (%), 0.41% for Hemoglobin (g/L), 0.21% for Platelet (× 109/L), 3.11% for D-dimer (mg/L), 84.06% for GGT, 4.14% for Albumin (g/L), 1.86% for ALT (U/L), 1.66% for Creatinine (umol/L), 19.05% for CKMB, 14.08% for cTnI (ng/mL), 19.67% for NT-proBNP (pg/mL), 1.04% for Serum potassium (mmol/L), 0.62% for Blood glucose, 8.28% for PH, 8.90% for SaO2, 58.18% for sPAP(mmHg), and 42.86% for RVD
  3. PTE pulmonary thromboembolism, DVT deep vein thrombosis, CPR cardiopulmonary resuscitation, b.p.m beats per minute, ALT alanine aminotransferase, GGT glutamyl transferase, Cr creatinine, CKMB creatine kinase-Mb, cTnI cardiac troponin I, NT-proBNP N-terminal pro-brain natriuretic peptide, SaO2 arterial oxygen saturation, sPAP systolic pulmonary artery pressure, RVD right ventricular dysfunction, PESI pulmonary thromboembolism severity index