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Table 2 The plasma levels of HDL-C and key HDL-related proteins

From: The HDL from septic-ARDS patients with composition changes exacerbates pulmonary endothelial dysfunction and acute lung injury induced by cecal ligation and puncture (CLP) in mice

 

ARDS patients (n = 40)

Healthy controls (n = 40)

P

HDL-C, mmol/Lb

0.55 (0.40–0.88)

1.46 (1.15–1.92)

 < 0.0001

apoA-I, μg/mlb

35.6 (24.0–43.0)

88.5 (70.3–111.7)

 < 0.0001

apoA-II, μg/mlb

32.0 (22.3–45.9)

58.0 (48.3–70.9)

 < 0.0001

apoA-IV, μg/mlb

7.5 (3.8–13.3)

28.7 (24.1–35.5)

 < 0.0001

apoC-III, μg/mlb

22.6 (21.1–25.0)

25.9 (23.7–28.7)

 < 0.0001

apoE, μg/mla

28.5 ± 1.0

20.6 ± 0.8

 < 0.0001

MPO, μg/mlb

0.6 (0.3–1.0)

0.7 (0.4–1.0)

0.61

PON1, ng/mlb

5.5 (4.2–7.1)

7.0 (6.1–9.1)

 < 0.0001

MPO/PON1b

105.8 (41.1–193.8)

91.9 (58.8–129.6)

0.28

  1. aStudent's-t test, bMann–Whitney U test. HDL-C high density lipoprotein-cholesterol, apo apolipoprotein, MPO myeloperoxidase, PON1 paraoxonase-1
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Respiratory Research

ISSN: 1465-993X

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