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Fig. 2 | Respiratory Research

Fig. 2

From: Small airway dysfunction as predictor and marker for clinical response to biological therapy in severe eosinophilic asthma: a longitudinal observational study

Fig. 2

comparative linear regressions: between small airway dysfunction (FDR, KPa/L/s) and airflow limitation (FEV1, ml) in correlation to ACT score (points) and reduction in exacerbations (%). All values represent the difference (delta) between baseline and under therapy. A: linear regression between (delta ACT) scores on the x-axis, and the change in FDR (delta R5-20), y-axis: R2 = 0.42, DF = 18, p = 0.001. B: linear regression between (delta ACT) scores on the x-axis and the change in FEV1 (delta FEV1), y-axis: R2 = 0.25, DF = 18, p = 0.013. C: linear regression between (delta exacerbations) on the x-axis and the change in FDR (delta FEV1), y-axis: R2 = 0.41, DF = 18, p = 0.001. D: linear regression between (delta exacerbations) on the x-axis and the change in FEV1 (delta R5-20), y-axis: R2 = 0.20, DF = 18, p = 0.025

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