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Table 1 Modeling differences in ACE2, TMPRSS2, BSG and FURIN expression accounting for proband age and sex

From: Expression of SARS-CoV-2 entry receptors in the respiratory tract of healthy individuals, smokers and asthmatics

gene

Adjusted p-value smokers vs. non-smokers

β smokers vs. non-smokers

Adjusted p-value asthmatics vs. healthy

β asthmatics vs. healthy

ACE2

6.80E-16

0.36

0.186

−0.074

TMPRSS2

0.00044

0.1

0.0156

0.13

BSG

0.31

−0.065

0.59

0.038

FURIN

0.31

0.047

0.29

0.048

  1. Adjusted p-values and linear regression model coefficients (β), testing hypotheses whether expression of ACE2, TMPRSS2, BSG and FURIN differ between smokers vs. non-smokers (columns 1,2) and asthmatics vs. healthy individuals (columns 3,4). The linear regression models were controlled for the linear effect of age, sex, sample type, and dataset
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Respiratory Research

ISSN: 1465-993X

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