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Table 1 Adaptive servo-ventilation settings for the OTRLASV population based on initial sleep-disordered-breathing diagnostic groups

From: Patterns of adaptive servo-ventilation settings in a real-life multicenter study: pay attention to volume!

 

Total

n = 177 (100%)

CSA group

n = 105 (59.3%)

OSA group

n = 36 (20.3%)

TECSA group

n = 36 (20.3%)

P

Fixed EPAP (cmH2O)b

n = 121

n = 76

n = 22

n = 23

 

6.00

5.50

6.00

7.00

0.458

[5.00–9.00]

[5.00–9.00]

[5.00–8.00]

[5.00–10.00]

 

(4.00–14.00)

(4.00–14.00)

(4.00–12.00)

(4.00–14.00)

 

Auto-EPAP (cmH2O)b

n = 56

n = 29

n = 14

n = 13

 

EPAPmin

4.00

4.00

5.00

5.00

0.143

[4.00–5.50]

[5.00–5.00]

[4.00–6.00]

[4.00–5.00]

 

(4.00–13.00)

(4.00–13.00)

(4.00–8.00)

(4.00–10.00)

 

EPAPmax

10

10

10

9

0.176

[8.00–12.00]

[8.00–10.00]

[10.00–12.00]

[7.00–12.00]

 

(3.00–18.00)

(5.00–15.00)

(5.00–15.00)

(3.00–18.00)

 

IPS (cmH2O)b

n = 176

n = 104

n = 36

n = 36

 

IPSmin

3.00

3.00

3.00

3.00

0.284

[0.00–3.00]

[3.00–3.00]

[0.00–5.00]

[0.00–3.00]

 

(0.00–15.00)

(0.00–15.00)

(0.00–13.00)

(0.00–7.50)

 

IPSmax

10

10

10

10

0.400

[9.00–10.00]

[10.00–10.00]

[8.00–11.00]

[8.50–10.00]

 

(3.00–20.00)

(6.00–20.00)

(3.00–17.00)

(5.00–15.00)

 

Pmax (cmH2O)b

n = 129

n = 76

n = 27

n = 26

 

19

19

17

19.5

0.317

[16.00–21.00]

[16.00–21.00]

[14.00–20.00]

[18.00–22.00]

 

(11.00–25.00)

(12.00–25.00)

(12.00–25.00)

(11–25.00)

 

Fixed backup RRb (cycle/min)

n = 39

n = 25

n = 8

n = 6

 

12

12

11.5

11.5

0.458

[11.00–12.00]

[12.00–12.00]

[10.00–12.50]

[10.00–12.00]

 

(8.00–16.00)

(8.00–14.00)

(10.00–16.00)

(10.00–22.00)

 

Auto backup RRb

n = 174

n = 104

n = 35

n = 35

0.697

135 (77.59%)

79 (75.96%)

27 (77.14%)

29 (82.86%)

 

Slope levelc

n = 42

n = 24

n = 9

n = 9

 

2

2

2

2

0.951

[2.00–3.00]

[2.00–3.00]

[2.00–3.00]

[2.00–3.00]

 

(1.00–6.00)

(1.00–6.00)

(1.00–3.00)

(1.00–3.00)

 

Ti minc (second)

n = 38

n = 25

n = 7

n = 6

 

1.65

1.70

1.70

1.70

0.929

[1.40–1.80]

[1.40–1.80]

[1.50–1.80]

[1.20–1.80]

 

(1.00–2.20)

(1.00–2.20)

(1.00–2.00)

(1.20–2.10)

 

Interface

n = 177

n = 105

n = 36

n = 36

 

Oronasal

89 (50.28%)

53 (50.48%)

13 (36.11%)

23 (63.89%)

0.062

Nasal

81 (45.76%)

49 (46.67%)

20 (55.56%)

12 (33.33%)

0.160

Nasal Pillows

9 (5.08%)

4 (3.81%)

4 (11.11%)

1 (2.78%)

0.254

Heated humidifier

n = 177

n = 105

n = 36

n = 36

 

127 (71.75%)

70 (66.67%)

27 (75.00%)

30 (83.33%)

0.142

Heated breathing tube

n = 177

n = 105

n = 36

n = 36

 

47 (26.55%)

20 (19.05%)a

18 (50.00%)a

9 (25.00%)

0.001

  1. Quantitative variables were summarized using medians, [IQ25–75] and (min – max), while categories were described by numbers and (%). The total percentage for interfaces is > 100% because multiple interfaces were used by 2 patients
  2. Significant pairwise comparisons with Holm corrections are presented a for CSA vs. OSA groups
  3. CSA Central sleep apnea, EPAP Expiratory positive airway pressure, IPS Inspiratory pressure support, max maximum, min minimum, OSA Obstructive sleep apnea, Pmax maximum pressure, RR Respiratory rate, TECSA Treatment emergent central sleep apnea, Ti min Inspiratory support minimum pressurization time
  4. bFor ASV-setting variables shared by both manufacturers, the data were pooled (EPAP (fixed or minimum/maximum); IPS (minimum and maximum), Pmax, RR or auto RR)
  5. cFor slope level and minimum inspiratory time, the data concern only Philips Respironics devices