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Table 3 Comparison of OCS maintenance SA patients with BEC < 400 or BEC ≥ 400 (n = 174)

From: Chronic oral corticosteroids use and persistent eosinophilia in severe asthmatics from the Belgian severe asthma registry

Characteristics

BEC < 400

BEC ≥400

P-value

N (%)

95 (55)

79 (45)

N/A

Age of onset (%) (yr) (n = 173)

  < 12

25 (27)

6 (8)

0.000

 12–40

37 (39)

26 (33)

  > 40

32 (34)

47 (59)

ACQ (n = 61)

2.97 ± 1.29

2.40 ± 1.37

0.0367

FEV1 (% predicted) (n = 110)

63.7 ± 23.6

71.7 ± 22.4

0.0267

FVC (% predicted) (n = 110)

83 ± 21

93 ± 23

0.0088

Sputum eosinophils (%) (n = 38)

2.8 (0.4–10.0)

46.5 (4.7–66.8)

0.0223

Sputum neutrophils (%) (n = 38)

70.0 (54.0–80.0)

21.7 (9.5–40.5)

0.0004

Exhaled NO (50 ml/sec) (ppb) (n = 67)

23 (13–42)

38 (19–83)

0.0005

Emphysema (based on Chest CT Scanner) (n = 174)

15 (16)

7 (9)

0.025

Nasal polyposis (n = 174)

25 (26)

33 (42)

0.042

Psychopathology (n = 174)

25 (26)

9 (11)

0.004

  1. Data are presented as mean ± SD or median and IQR. FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, ppb parts per billion, NO nitric oxide, ppb parts per billion, ACQ Asthma Control Questionnaire, N/A not applicable