Fig. 1
From: The SPLUNC1-βENaC complex prevents Burkholderia cenocepacia invasion in normal airway epithelia
SPLUNC1 knockout mice have increased susceptibility to J2315 infection. Male and female SPLUNC1−/− and wild-type littermate mice were infected intratracheally with 5 × 107 CFU/mouse J2315. 24 h after infection, mice were euthanized and (a) BAL and (b) whole lung were collected. Whole lung was homogenized and aliquots of lung and BAL were serially diluted and plated to determine bacterial counts. N = 6–8 mice per group. * = p < 0.05, ** = p < 0.01