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Fig. 4 | Respiratory Research

Fig. 4

From: In vivo miR-138-5p inhibition alleviates monocrotaline-induced pulmonary hypertension and normalizes pulmonary KCNK3 and SLC45A3 expression

Fig. 4

In vivo inhibition of miR-138-5p reduces the pulmonary vascular cell proliferation in MCT-PH rats.a Immunofluorescence staining of frozen rat lung sections and confocal imaging with Click-iT 5-ethynyl-2′-deoxyuridine (EdU; white nuclei = EdU-positive nuclei = proliferating cells, yellow arrow) in combination with α-smooth muscle actin (α-SMA; in green, CD34; in red). Scale bar = 20 μm. The cells were counterstained with DAPI (blue). b Quantification of the percentage of proliferating cells in the lungs. (n = 6 different rats per condition). *P < 0.05, **P < 0.01

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Respiratory Research

ISSN: 1465-993X

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