Fig. 2

a: The proportion of individuals recorded as having died at the end of follow up (black) plotted against their index blood eosinophil count. The red symbols are proportions (out of all individuals) with death from a cause recorded as falling within ICD10 category J44 (COPD). b: Distribution of blood neutrophil counts (BNCs) showing all values (hollow bars); all measurements from individuals with stable and exacerbating results available (black bars) and measurements made during exacerbations (red bars). The black dots show the proportion of BNCs made outside of exacerbation periods. Three vertical dotted lines indicate the cut-offs applied to separate BNCs into normal (<6000cells/μL), elevated (6000–15,000cells/μL) and extreme (> 15,000cells/μL) c: The proportion of individuals recorded as having died by the end of follow up (black) plotted against their index BNC. The red symbols are proportions (out of all individuals) with death from a cause recorded as falling within ICD10 category J44. Three vertical dotted lines indicate the cut-offs applied to separate BNCs into low (<2000cells/μL), normal (2000–6000cells/μL) and elevated 6000–15,000cells/μL) d: as C, but using the last BNC recorded for each individual. Solid points are based on final stable BNC, while hollow ones include BNC recorded during exacerbations