Fig. 1

Kaplan-Meier survival curve of pre-PERT-era and PERT-era cohorts (a) and prevalence of severity of markers among the 2 cohorts (b). Hi-Flo, high-flow oxygen nasal cannula (> 15 L per minute); MV, mechanical ventilation, hypotension is defined as systolic blood pressure between 100-110mmHG and 40 mmHg lower than at baseline; shock is defined as hypotension requiring vasopressor medication. * p = < 0.05 by Chi square test