Skip to main content

Table 2 Demographic and sleep characteristics of all participants stratified by total sleep duration categories

From: Interaction between obstructive sleep apnea and short sleep duration on insulin resistance: a large-scale study

Characteristics

> 8 h

(n = 538)

7-8 h

(n = 1757)

6-7 h

(n = 1710)

5-6 h

(n = 841)

≤5 h

(n = 601)

P

Demographic and clinical characteristics

 Men,n(%)

441 (81.97)

1457 (82.93)

1387 (81.11)

676 (80.38)

471 (78.37)

0.1297

 Age (years)

42.88 ± 11.53

42.18 ± 11.50

42.24 ± 11.59

43.02 ± 12.03

44.11 ± 13.05

0.0045*

 Neck circumference (cm)

39.91 ± 3.92

39.47 ± 3.52

39.35 ± 3.77

39.18 ± 3.70

38.78 ± 3.65

<.0001*

 Waist circumference (cm)

97.78 ± 12.15

96.09 ± 10.50

95.31 ± 11.16

94.86 ± 11.48

93.27 ± 11.20

<.0001*

 Hip circumference (cm)

102.63 ± 8.28

101.57 ± 7.77

101.26 ± 8.05

100.77 ± 8.01

99.83 ± 7.51

<.0001*

 Waist hip ration

0.95 ± 0.07

0.95 ± 0.22

0.94 ± 0.22

0.94 ± 0.07

0.93 ± 0.07

0.2733

 BMI (kg/m2)

27.44 ± 4.37

26.89 ± 3.91

26.69 ± 4.04

26.42 ± 3.88

25.99 ± 3.80

<.0001*

 Hypertension, n (%)

154 (28.62)

459 (26.12)

431 (25.20)

199 (23.66)

153 (25.46)

0.0005*

 SBP (mmHg)

127.84 ± 15.31

127.36 ± 15.86

125.46 ± 15.38

126.24 ± 15.76

125.57 ± 15.91

0.3267

 DBP (mmHg)

82.90 ± 11.81

81.96 ± 11.68

80.77 ± 11.66

81.07 ± 11.57

80.09 ± 11.01

<.0001*

 Diabetes mellitus, n (%)

54 (10.04)

158 (8.99)

132 (7.72)

61 (7.25)

42 (6.99)

0.1603

 Hyperlipidemia,n (%)

421 (78.25)

1410 (80.25)

1304 (76.26)

641 (76.22)

451 (75.04)

0.0160*

 Smoking, n (%)

250 (46.47)

765 (43.54)

697 (40.76)

314 (37.34)

178 (29.62)

<.0001*

 Alcohol consumption, n(%)

69 (12.83)

181 (10.30)

203 (11.87)

80 (9.51)

43 (7.15)

0.0059*

 Fasting glucose (mmol/l)

5.67 ± 1.38

5.57 ± 1.30

5.47 ± 1.22

5.48 ± 1.22

5.40 ± 1.15

0.0006*

 Fasting insulin (μU/ml)

10.93 (7.74,16.52)

11.20 (7.59,16.22)

10.89 (7.13,16.26)

11.11 (7.04,16.90)

10.47 (6.96,15.61)

0.1768

 HOMA-IR

2.57 (1.78,4.19)

2.65 (1.73,4.17)

2.56 (1.60,4.03)

2.63 (1.59,4.14)

2.50 (1.55,3.94)

0.0313*

 Cholesterol (mmol/l)

4.85 ± 0.94

4.80 ± 1.02

4.75 ± 0.96

4.81 ± 1.02

4.81 ± 1.12

0.2433

 Triglyceride (mmol/l)

2.17 ± 2.03

2.11 ± 1.88

2.01 ± 1.80

2.03 ± 1.83

1.91 ± 1.46

0.0633

 High density lipoprotein (mmol/l)

1.04 ± 0.23

1.04 ± 0.24

1.07 ± 0.25

1.10 ± 0.26

1.12 ± 0.30

<.0001*

 Low density lipoprotein (mmol/l)

2.95 ± 0.76

2.97 ± 0.82

2.99 ± 0.82

3.03 ± 0.83

3.07 ± 0.97

0.0471*

 ApolipoproteinA-1(g/l)

1.06 ± 0.18

1.05 ± 0.18

1.08 ± 0.20

1.09 ± 0.21

1.10 ± 0.21

<.0001*

 Apolipoprotein-B (g/l)

0.88 ± 0.21

0.88 ± 0.21

0.85 ± 0.20

0.85 ± 0.20

0.85 ± 0.22

<.0001*

 Apolipoprotein-E (mg/dl)

4.76 ± 2.14

4.72 ± 2.56

4.61 ± 1.96

4.75 ± 2.10

4.61 ± 1.70

0.3730

 Lipoprotein-α (mg/dl)

13.78 ± 15.85

12.59 ± 15.06

11.99 ± 13.93

12.52 ± 14.71

13.50 ± 16.72

0.0839

 ESS

9.01 ± 5.70

8.97 ± 5.96

8.55 ± 5.83

7.97 ± 5.76

7.73 ± 5.74

<.0001*

 ESS > 10, n(%)

203 (37.73)

670 (38.13)

629 (36.78)

259 (30.80)

179 (29.78)

<.0001*

Polysomnography

 Total sleep duration, min

501.31 ± 17.48

447.95 ± 16.64

394.27 ± 17.51

333.97 ± 16.91

235.34 ± 58.19

<.0001*

 Total time in bed, min

547.02 ± 71.76

512.54 ± 89.05

480.98 ± 83.65

472.24 ± 99.31

445.39 ± 124.62

<.0001*

 Sleep efficiency,%

0.92 ± 0.07

0.89 ± 0.09

0.84 ± 0.11

0.73 ± 0.12

0.56 ± 0.18

<.0001*

 S1(% TST)

16.08 ± 12.44

16.50 ± 13.11

17.04 ± 13.70

20.47 ± 13.99

22.70 ± 16.36

<.0001*

 S2(% TST)

53.30 ± 16.15

50.09 ± 19.99

47.61 ± 20.75

48.46 ± 17.41

46.74 ± 19.14

<.0001*

 S3(% TST)

15.24 ± 11.36

13.42 ± 10.52

12.70 ± 10.64

13.69 ± 10.80

13.17 ± 12.04

0.0001*

 REM(% TST)

12.23 ± 6.49

10.89 ± 6.56

10.60 ± 6.76

10.15 ± 6.35

9.38 ± 7.42

<.0001*

 AHI (events/h)

40.93 ± 27.23

37.10 ± 27.51

34.97 ± 27.60

31.08 ± 27.10

28.66 ± 26.16

<.0001*

 Lowest-SpO2,%

74.05 ± 13.93

75.96 ± 14.47

77.81 ± 13.97

79.87 ± 14.58

81.65 ± 15.00

<.0001*

 ODI

41.40 ± 29.11

37.32 ± 28.60

35.17 ± 28.66

32.76 ± 28.96

31.33 ± 28.31

<.0001*

 Mean SaO2

93.11 ± 3.93

93.62 ± 3.55

93.83 ± 3.68

94.34 ± 2.94

94.60 ± 2.71

<.0001*

 OSA, n (%)

466 (86.62)

1493 (84.97)

1411 (82.51)

680 (80.86)

457 (76.04)

<.0001*

 Mild OSA, n (%)

57 (10.59)

262 (14.90)

284 (16.61)

163 (19.38)

112 (18.64)

<.0001*

 Moderate OSA, n (%)

80 (14.87)

268 (15.25)

273 (15.96)

164 (19.50)

106 (17.64)

0.0514

 Severe OSA, n (%)

329 (61.15)

963 (54.81)

854 (49.94)

353 (41.97)

239 (39.77)

<.0001*

 MAI

31.44 ± 21.41

28.78 ± 21.37

29.24 ± 22.57

28.86 ± 22.19

27.70 ± 20.03

0.0552

  1. Acronyms: OSA Obstructive sleep apnea, BMI Body mass index, HOMA-IR Homeostasis model assessment for insulin resistance, SBP Systolic blood pressure, DBP Diastolic blood pressure, ESS Epworth Sleepiness Scale, AHI Apnea–hypopnea index, TST Total sleep time, REM Rapid eye movement, LSpO2 Lowest oxygen saturation, ODI Oxygen desaturation index, SaO2 Oxygen saturation
  2. The data are presented as means and standard deviation (SD) and categorical data as the number (percentage)
  3. Differences in the baseline characteristics among the five groups were examined using the polynomial linear trend test for continuous variables and the linear-by-linear association test for dichotomous variables
  4. * p indicates a significant difference