Table 1 Difference between mild and severe patients based on initial symptom and serum biochemical examination
Variables | All (n = 123) | Mild (n = 95) | Severe (n = 28) | P |
|---|---|---|---|---|
Characteristic | ||||
Age (years) | 37 (7) | 35 (6) | 39.5 (5.35) | 0.019 |
Sex (male) | 55/123 (44.7%) | 38/95 (40%) | 17/28 (60.7%) | 0.053 |
Signs and symptoms | ||||
Temp(°C) | 38.20 (0.80) | 38.10 (0.8) | 38.50 (0.50) | 0.036 |
Time pre-adm (days) | 6 (4) | 7 (4) | 6.00 (2.50) | 0.297 |
Fever | 98/123 (79.7%) | 71/95 (74.7%) | 27/28 (96.4%) | 0.012 |
Cough | 79/123 (64.2%) | 64/95 (67.4%) | 15/28 (53.6%) | 0.181 |
Expectoration | 32/123 (26%) | 23/95 (24.2%) | 9/28 (32.1%) | 0.400 |
Headache | 19/123 (15.4%) | 15/95 (15.8% | 4/28 (14.3%) | 0.847 |
Wheeze | 24/123 (19.5%) | 18/95 (18.9%) | 6/28 (21.4%) | 0.771 |
Weakness | 50/123 (40.7%) | 36/95 (37.9%) | 14/28 (50%) | 0.252 |
Muscle ache | 31/123 (25.2%) | 25/95 (26.3%) | 6/28 (21.4%) | 0.601 |
Pharyngalgia | 12/123 (9.8%) | 9/95 (9.5%) | 3/28 (10.7%) | 0.846 |
Runny nose | 2/123 (1.6%) | 2/95 (2.1%) | 0/28 (0%) | 0.439 |
Anorexia | 59/123 (48.0%) | 38/95 (40%) | 21/28 (75%) | 0.001 |
Stethalgia | 10/123 (8.1%) | 9/95 (9.5%) | 1/28 (3.6%) | 0.315 |
Chest Tightness | 39/123 (31.7%) | 28/95 (29.5%) | 11/28 (39.3%) | 0.327 |
Dyspnea | 7/123 (5.7%) | 5/95 (5.3%) | 2/28 (7.1%) | 0.706 |
Diarrhea | 13/123 (10.6%) | 9/95 (9.5%) | 4/28 (14.3%) | 0.467 |
CT Bilateral Lesion | 84/123 (68.3%) | 63/95 (66.3%) | 21/28 (75%) | 0.385 |
Preadmission Drugs | 49/123 (39.8%) | 40/95 (42.1%) | 9/28 (32.1%) | 0.344 |
Serum Biomarkers | ||||
WBC(109/L) | 4.85 (1.04) | 5.01 (0.93) | 3.97 (1.37) | 0.048 |
RBC(109/L) | 4.49 (0.40) | 4.47 (0.39) | 4.69 (0.45) | 0.102 |
N% | 63.77 (15.16) | 61.99 (13.93) | 69.81 (17.72) | 0.016 |
N(109/L) | 2.96 (0.89) | 3.01 (0.77) | 2.57 (1.81) | 0.563 |
L(109/L) | 1.22 (0.41) | 1.30 (0.56) | 0.80 (0.36) | < 0.001 |
PLT(109/L) | 173 (39) | 184 (42) | 157.50 (23.00) | 0.016 |
CRP (mg/dL) | 0.58 (1.66) | 0.46 (0.93) | 1.46 (2.58) | < 0.001 |
Cr (umol/L) | 64.50 (8.30) | 63.30 (9.20) | 66.35 (10.63) | 0.433 |
BUN (mmol/L) | 3.62 (0.58) | 3.62 (0.56) | 3.83 (1.23) | 0.173 |
AST(U/L) | 20.00 (6.20) | 19.00 (6.30) | 22.45 (11.83) | 0.037 |
ALT(U/L) | 18.50 (11.20) | 17.70 (12.00) | 24.05 (7.78) | 0.094 |
TBIL (umol/L) | 8.80 (3.40) | 8.80 (2.60) | 8.65 (3.80) | 0.686 |
DBIL (umol/L) | 3.00 (0.90) | 3.00 (0.80) | 3.05 (1.43) | 0.319 |
IBIL (umol/L) | 5.60 (2.60) | 5.60 (2.60) | 5.75 (3.43) | 0.959 |
ALB(g/L) | 41.96 (4.62) | 42.42 (4.48) | 40.40 (4.82) | 0.042 |
CK(U/L) | 67 (51) | 64.50 (45.75) | 92.00 (106.00) | 0.011 |
CK-MB(U/L) | 7.00 (3.00) | 6.90 (3.70) | 8.00 (2.00) | 0.243 |
D-dimer (mg/dL) | 0.32 (0.28) | 0.30 (0.46) | 0.37 (0.15) | 0.574 |
PT(s) | 16.20 (0.60) | 16.20 (0.60) | 15.8 (1.20) | 0.330 |
INR | 0.98 (0.07) | 0.99 (0.07) | 0.98 (0.07) | 0.414 |
Fib(g/L) | 2.52 (0.42) | 2.50 (0.30) | 2.75 (0.76) | 0.001 |