Immunoreactivity to metal and silica associates with sarcoidosis in Dutch patients

Respiratory Research

Table 1 Demographics of sarcoidosis and control patients

	Controls (%) (n = 73)	Sarcoidosis (%) (n = 256)	P*
Male / Female	64.4 / 35.6	63.7 / 36.3	0.91
Age at diagnosis (Y)	N/A	43.57 ± 10.63	–
Age at inclusion (Y)	55.42 ± 14.37	54.50 ± 10.83	0.61
Ethnicity (W/B/O)	93.2 / 2.7 / 4.1	93.4 / 3.5 / 3.1	0.88
Smoking status ^a
(Never/former or current)	34.2 / 65.8	57.7 / 42.3	< 0.001
Scadding stage at inclusion
(0/I/II/III/IV/ unknown)	N/A	30.1 / 9.8 / 18.4 / 12.9 / 26.2 / 2.7
Extra pulmonary involvement		46.5

Age at diagnosis and age at inclusion are shown as means ± std. deviation. Scadding stages were determined by chest X-ray. If Scadding stages at the time of inclusion were not available, Scadding stage was determined from the last obtained chest X-ray before the inclusion date. 0 = Normal chest radiograph; I = Bilateral hilar lymphadenopathy (BHL); II = BHL with pulmonary infiltrates; III = pulmonary infiltrates without BHL; IV = fibrosis.
B Black, O Other, W White
^a Smoking status was not available from 8 sarcoidosis patients. *Statistical differences for sex, ethnicity and smoking status were accessed using Pearson Chi-Square, statistical differences for age were calculated using an unpaired T-test

ISSN: 1465-993X