Compared to plasma, bronchial washing fluid shows higher diagnostic yields for detecting EGFR-TKI sensitizing mutations by ddPCR in lung cancer

Table 3 Sensitivity, specificity, and concordance rate of ddPCR according to lung cancer stage

	Early stage of lung cancer (n = 38)			Advanced stage of lung cancer (n = 35)
	Plasma	BWF	p-value	Plasma	BWF	p-value
AUC	0.504 (0.338–0.670)	0.768 (0.603–0.889)	0.008	0.879 (0.724–0.964)	1.0 (0.899–1.000)	0.043
Sensitivity (%)	15.0	65.0		72.2	100.0
Specificity (%)	100.0	88.9		100.0	100.0

Note: Early stage refers to stage I - IIIA, and advanced stage refers to stage IIIB - IV
Abbreviation: BWF, bronchial washing fluid; AUC, area under curve

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