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Fig. 3 | Respiratory Research

Fig. 3

From: A phase IIb, randomised, parallel-group study: the efficacy, safety and tolerability of once-daily umeclidinium in patients with asthma receiving inhaled corticosteroids

Fig. 3

LS mean change from baseline in home spirometry measures and E-RS total scores. LS mean (95% CI) change from baseline in (a) home trough FEV1 up to Week 8 by 1-weekly intervals, (b) home trough FEV1 over the 24-week treatment period by 4-weekly intervals, (c) AM PEF over the 24-week treatment period by 4-weekly intervals and (d) E-RS total scores over the 24-week treatment period by 4-weekly intervals (ITT population). Error bars represent 95% CI. *p≤0.05; **p≤0.01; ***p≤0.001, treatment difference from placebo. AM, morning; CI, confidence interval; E-RS, Evaluating Respiratory Symptoms; FEV1, forced expiratory volume in 1 s; ITT, intent-to-treat; LS, least squares, PEF, peak expiratory flow; UMEC, umeclidinium

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