Fig. 5

Sub-chronic e-cig exposure lead to dysregulateddifferentially affects the protein abundance of NF-κB subunits (p50/p105) and Angiotensin-converting enzyme 2 (ACE2) in mouse lungs with sex differences. The protein abundance of (a) p50/p105 and (b) Angiotensin-converting enzyme 2 (ACE2) were measured in whole lung homogenates via Western blot. Representative blot images for female and male mice are shown. Densitometry analysis of individual blots was performed for p50/p105 and ACE2 for both female and male, and β-actin was used as an endogenous control. Data are shown as mean ± SEM. (n=4-5/group). * P < 0.05 significant compared between groups; P < 0.05, compared with air exposed WT group; # P < 0.05, compared with PG+Nic exposed WT group