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Fig. 6 | Respiratory Research

Fig. 6

From: IRF4 and STAT3 activities are associated with the imbalanced differentiation of T-cells in responses to inhalable particulate matters

Fig. 6

The levels of phosphorylated Stat3 and Irf4 increases in mice lung tissues in response to PM exposure in vivo. Two groups of six BALB/c mice were treated with PM suspension for 3 days then after 24 h the lung tissue were collected for Western Blot assay. a, Western Blot showing the protein expression levels of phosphorylate-Stat3 (pStat3), un-phospho-Stat3 (Stat3), phosphorylate-Irf4 (pIrf4), un-phospho-Irf4 (Irf4) with beta-actin as control; b, the ratios of phosphorylate-Stat3 versus un-phospho-Stat3 and phosphorylate-Irf4 versus un-phospho-Irf4 increase significantly in response to PM treatment (* P < 0.05, ** P < 0.01, *** P < 0.001)

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