Table 1 Demographics of ARDS patients and healthy controls

Numbers

28

42

27

15

Age (year)

62.3 ± 15.3

64.2 ± 14.0

63.07 ± 15.5

66.3 ± 10.9

0.48

Gender, Female, n (%)

17 (60.7%)

28 (66.7%)

19 (70.4%)

9 (69.2%)

0.36

 Pneumonia

27 (64.3%)

18 (66.7%)

9 (60%)

0.74

 Aspiration

1 (2.4%)

0 (0%)

1 (6.7%)

0.38

 Extrapulmonary sepsis

6 (14.3%)

4 (14.8%)

2 (13.3%)

0.64

 Pancreatitis

48 (8.9%)

3 (11.1%)

1 (6.7%)

0.55

 Trauma or hemorrhagic shock

2 (4.8%)

1 (3.7%)

1 (6.7%)

0.59

 others

2 (4.8%)

1 (3.7%)

1 (6.7%)

0.59

 Mild

7 (16.7%)

4 (14.8%)

3 (20%)

0.69

 Moderate

24 (57.1%)

19 (70.4%)

5 (18.5%)

0.02#

 Severe

11 (26.2%)

4 (14.8%)

7 (25.9%)

0.07

 APACHE II score

17.1 ± 6.5

15.6 ± 6.1

19.7 ± 6.7

0.05*

 PaO2/FiO2

153.5 ± 68.3

167.6 ± 62.9

128.1 ± 72.3

0.07

 CRP, mg/dL

97.3 ± 69.5

100.0 ± 63.0

91.9 ± 83.0

0.73

 PCT, ng/mL

46.5 ± 84.8

52.9 ± 93.0

34.9 ± 69.4

0.52

 Leukocytes, × 10⁹/L

12.6 ± 5.9

13.1 ± 5.8

11.8 ± 6.1

0.50

 Neutrophils, ×10⁹/L

11.1 ± 5.4

12.0 ± 5.8

9.4 ± 4.4

0.16

 Lymphocytes, ×10⁹/L

2.3 ± 2.9

2.5 ± 3.2

1.9 ± 2.1

0.51

 Albumin (g/L)

51.6 ± 53.5

50.8 ± 56.9

52.8 ± 50.4

0.93

 Prealbumin (mg/L)

94.6 ± 54.5

100 ± 55.1

86.5 ± 55.0

0.52

 Ventilator free days

7.5 ± 13.2

9.6 ± 12.7

3.7 ± 13.7

0.17

 ICU stay, days

32.4 ± 26.8

25.8 ± 30.8

23.1 ± 16.9

0.33

 Vt/ Bwt

7.03 ± 1.8

7.2 ± 2.0

6.9 ± 1.5

0.72

 Inhaled nitric oxide therapy

0

0

0

/

 Prone position

4 (9.5%)

4 (14.8%)

0

0.28

 ECMO

2 (4.8%)

1 (3.7%)

1 (6.7%)

1.0