Table 1 Baseline characteristics of the survivors and non-survivors with acute respiratory distress syndromea
Survivor(n = 32) | Non-survivor(n = 84) | p-value | |
|---|---|---|---|
Male, N(%) | 24 (75.0) | 57 (67.9) | 0.454 |
Age, mean ± SD | 64.5 ± 17.1 | 66.7 ± 13.2 | 0.459 |
Underlying disease, N(%) | |||
Diabetes | 7 (21.9) | 24 (28.6) | 0.466 |
Hypertension | 12 (37.5) | 26 (31.0) | 0.502 |
Tuberculosis | 1 (3.1) | 10 (11.9) | 0.285 |
Chronic liver disease | 1 (3.1) | 5 (6.0) | 1.000 |
Cause of ARDS, N(%) | |||
Pneumonia | 25 (78.1) | 63 (75.0) | 0.812 |
Aspiration | 3 (9.4) | 5 (6.0) | 0.683 |
Sepsis | 3 (9.4) | 8 (9.5) | 1.000 |
Transfusion | 0 (0) | 1 (1.2) | 1.000 |
Others | 1 (3.1) | 7 (8.3) | 0.442 |
Disease severity, mean ± SD | |||
SAPS II | 75.0 ± 22.0 | 79.0 ± 19.4 | 0.338 |
APACHE II | 31.8 ± 8.5 | 35.2 ± 8.1 | 0.047 |
SOFA | 13.7 ± 4.0 | 13.6 ± 3.9 | 0.874 |
APPS, median ± IQR | 5.0, 4.3–6.0 | 6.0, 5.0–7.0 | < 0.001 |
Physiological parameters, mean ± SD | |||
pH, median ± IQR | 7.4, 7.3–7.4 | 7.3, 7.3–7.4 | 0.066 |
PaCO2 | 43.5 ± 14.6 | 45.8 ± 13.6 | 0.430 |
PaO2/FiO2 | 111.5 ± 40.8 | 103.4 ± 36.0 | 0.294 |
Ventilator parameters, mean ± SD | |||
Tidal volume (mL/kg PBW) | 7.1 ± 2.1 | 7.5 ± 2.6 | 0.503 |
Minute ventilation(L/min) | 10.4 ± 3.5 | 10.0 ± 3.5 | 0.649 |
FIO2 | 0.76 ± 0.18 | 0.82 ± 0.19 | 0.166 |
PEEP (cmH2O) | 7.2 ± 2.4 | 7.3 ± 2.6 | 0.859 |
Pmax (cmH2O) | 23.7 ± 4.9 | 24.7 ± 4.8 | 0.298 |