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Table 1 Characteristics of patients and healthy controls

From: Different expression levels of interleukin-35 in asthma phenotypes

Variable

Asthma

Normal

P value

Number

89

19

 

Age (years)

52.24 ± 13.32

44.58 ± 16.30

0.025

Sex, male (%)

37(41.6)

9 (47.4)

0.617

BMI (kg/m2)

23.86 ± 3.49

23.22 ± 3.28

0.589

Ex-smoker, n (%)

23 (25.8)

7 (36.84)

0.667

Smoking index

0 (0,15)

0 (0,5.25)

0.796

Post-FEV1 (L)

2.36 ± 1.00

3.13 ± 0.91

0.009

Post-FVC (L)

3.53 ± 1.20

3.65 ± 0.79

0.677

FeNO (ppd)

42.20 (27.80, 99.65)

22.5 (16.5, 24.00)

0.004

Sputum TCC (106/mL)

3.00 (1.80, 5.40)

2.43 (1.62, 3.24)

0.180

Sputum NEU (104/mL)

10 (1, 91)

0 (0, 6)

<  0.001

Sputum EOS (104/mL)

7 (0, 58)

0 (0, 2)

<  0.001

Sputum MA (106/mL)

1.34 (0.27, 3.52)

2.37 (1.56, 3.12)

0.100

Sputum LY (104/mL)

2.51 (0, 16.46)

5.49 (1.08, 12.96)

0.255

  1. Data are expressed as mean ± SD or median (IQR). Data were analyzed using a Student’s t-test or a Mann-Whitney U test and were adjusted for age. BMI Body mass index, FEV1 Forced expiratory volume in 1 s, FVC Forced vital capacity, FeNO Fractional exhaled nitric oxide, TCC Total cell count, NEU Neutrophils, EOS Eosinophils, MA Macrophages, LY: Lymphocyte