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Table 1 Baseline characteristics of total and different degrees of NT-proBNP

From: Prognostic value of NT-proBNP in patients with severe COVID-19

Characteristics Total (n = 54) NT-proBNP≤88.64 pg/ml (n = 24) NT-proBNP> 88.64 pg/ml (n = 30) P
Male/Female (n) 24/30 8/16 16/14 0.142
Age (years) 60.4 ± 16.1 51.6 ± 13.9 67.4 ± 14.4 < 0.001
Temperature (°C) 36.7 (36.5–36.9) 36.8 (36.5–36.9) 36.6 (36.5–36.9) 0.670
Pulse (/min) 82 (76–97) 84 (76–97) 82 (76–96) 0.679
Respire (/min) 20 (19–21) 20 (19–20) 20 (18–26) 0.209
SBP (mmHg) 128 (119–138) 126 (115–134) 129 (120–144) 0.218
DBP (mmHg) 78 (70–83) 73 (69–78) 80 (70–86) 0.040
History of HP (n) 12 (22.2%) 2 (8.3%) 10 (33.3%) 0.028
History of CHD (n) 9 (16.7%) 1 (4.2%) 8 (26.7%) 0.027
History of COPD (n) 2 (3.7%) 0 2 (6.7%) 0.197
History of DM (n) 8 (14.8%) 3 (12.5%) 5 (16.7%) 0.668
NT-proBNP (pg/ml) 137.30 (39.64–494.98) 37.28 (22.28–61.74) 420.40 (199.63–919.88) < 0.001
MYO (ng/ml) 39.28 (26.26–86.84) 25.35 (14.04–35.20) 82.53 (34.55–123.96) < 0.001
CK-MB (ug/L) 1.04 (0.65–2.27) 0.63 (0.37–0.79) 1.90 (1.08–3.78) < 0.001
Hs-TnI (ng/ml) < 0.006 (< 0.006–0.022) < 0.006 (< 0.006- < 0.006) 0.021 (< 0.006–0.136) 0.001
Urea (mmol/L) 4.8 (3.3–9.0) 3.4 (2.6–4.9) 7.1 (4.4–9.9) < 0.001
Creatinine (umol/L) 63 (44–77) 54 (41–69) 79 (55–86) 0.016
WBC (109/L) 5.42 (4.13–7.45) 5.89 (4.53–10.76) 5.73 (4.50–8.20) 0.007
LYM (109/L) 1.12 ± 0.52 1.30 ± 0.43 0.98 ± 0.55 0.021
CRP (mg/L) 34.8 (5.3–61.0) 7.6 (5.0–34.8) 54.3 (14.3–117.9) 0.003
PCT (ng/ml) 0.063 (0.029–0.171) 0.038 (0.020–0.058) 0.137 (0.049–0.468) < 0.001
In-hospital death (n) 18 (33.3%) 0 18 (60.0%) < 0.001
  1. Abbreviations: SBP Systolic blood pressure, DBP Diastolic blood pressure, HP Hypertension, CHD Coronary heart disease, COPD Chronic obstructive pulmonary disease, DM Diabetes mellitus, NT-proBNP N-terminal pro-brain natriuretic peptide, MYO Myoglobin, CK-MB creatine kinase-MB, Hs-TnI High-sensitivity troponin-I, WBC White blood cell, LYM Lymphocytes, CRP C-reactive protein, PCT Procalcitonin