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Fig. 2 | Respiratory Research

Fig. 2

From: A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor

Fig. 2

Summary of adjusted medians of uncorrected VT, (mL/cm3) of [18F]FBA20FMDV2 and individual patient profiles. PET1: PET scan on day 1 at ~30 min post-dose; PET2: PET scan on day 2 at ~24 h post-dose. The adjusted medians (with 95% Cr I) were calculated from a Bayesian repeated measures model using data from participants on the GSK3008348 1000 mcg arm only and is indicated by a thicker line and filled triangles. Data for individual participants dosed with GSK300834 are shown with dotted lines linking the data. Individual subject data is shown for participants on GSK3008348 1000 mcg (red symbols) and placebo (green symbols). The PET data from the placebo participants are included on plots for reference, but were not included in the analysis.

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Respiratory Research

ISSN: 1465-993X

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