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Fig. 5 | Respiratory Research

Fig. 5

From: SOD2 ameliorates pulmonary hypertension in a murine model of sleep apnea via suppressing expression of NLRP3 in CD11b+ cells

Fig. 5

Micro-PET scanning of in vivo 99mTc-labelled- MAG3-anti-CD11b in SOD2 deficiency mice. a. Representative radioactive heat map of WT and SOD2−/+ mice under condition of normal air and CIH. b. Lung mean-SUV value in the four groups. c. Total reserved SUV in the lung of WT and SOD2−/+ mice after CIH intervention. d. Cardiac mean-SUV value in the four groups. e. Total reserved SUV in the heart of WT and SOD2−/+ mice after CIH intervention. CON: Wild type mice in the normal air condition. CIH: Chronic intermittent hypoxia. WT: wild type mice. SOD2−/+: knock-down of SOD2 gene heterozygous mice. N = 5. Comparisons between multiple groups were performed using ANOVA with the Bonferroni test. *p < 0.05, **p < 0.01, ***p < 0.001

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