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Fig. 2 | Respiratory Research

Fig. 2

From: Comparative analyses of long non-coding RNA profiles in vivo in cystic fibrosis lung airway and parenchyma tissues

Fig. 2

Comparative analyses and classification of LncRNAs significantly altered in CF airway and parenchyma tissues. Venn diagrams indicate the differentially expressed (a) LncRNAs and b mRNAs that are common to airway and parenchyma tissues: up-regulated and down-regulated in CF compared to control tissues. The LncRNAs and mRNAs that exhibit similar expression pattern in the CF airway and parenchyma tissues are listed in the adjacent tables. The two LncRNAs that were validated in cell line models are highlighted. c The pie charts indicate the classification of the aberrantly expressed LncRNAs. The intergenic LncRNAs account for majority (58–63%) of the differences in CF airway as well as lung parenchyma tissues compared to non-CF control tissues

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