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Table 1 Effects of upper-airway surgery on components of MetS in patients with OSA with and without EDS

From: Excessive daytime sleepiness, metabolic syndrome, and obstructive sleep apnea: two independent large cross-sectional studies and one interventional study

 

OSA without EDS (n = 24)

OSA with EDS (n = 33)

Differences in after-before upper-airway surgery between patients with and without EDS (95%CI)

p value

Before upper-airway surgery

After upper-airway surgery

Before upper-airway surgery

After upper-airway surgery

Glucose(mmol/L)

5.43(0.72)

5.00(1.48)

5.28(0.69)

5.03(1.14)

−0.28(− 0.76~0.21)

0.61

Insulin(μU/mL)

10.50(4.95)

10.65(4.83)

15.83(11.05)

15.66(8.00)

−1.81(−4.51~0.89)

0.94

HOMA-IR

3.39(2.59)

2.79(2.14)

3.93(2.56)

3.33(2.86)

−0.60 (−1.21~0.01)

0.70

TC(mmol/L)

4.93(0.76)

4.83(0.84)

4.96(1.02)

4.57(0.76)

−0.33(−0.54~ − 0.12)

0.69

TG(mmol/L)

2.16(1.98)

2.55(3.69)

2.74(2.42)

2.19(0.95)

−0.03(− 0.82~0.76)

0.91

HDL(mmol/L)

1.06(0.21)

1.00(0.19)

1.14(0.29)

1.09(0.24)

−0.04(− 0.09~0.01)

0.70

LDL(mmol/L)

3.29(0.83)

2.95(0.65)

3.14(0.51)

2.87(0.63)

−0.31(− 0.51~ − 0.11)

0.86

SBP(mmHg)

126.00(13.23)

128.86(14.78)

128.80(15.88)

123.90(14.45)

−2.41(−8.75~3.93)

0.34

DBP(mmHg)

81.21(7.10)

82.64(11.02)

81.60(10.28)

78.15(9.09)

0.88(−5.23~7.03)

0.56

BMI(kg/m2)

28.26(4.93)

27.68(3.82)

28.36(2.85)

27.82(3.35)

−0.67(−1.05~ − 0.30)

0.38

WHR

0.96(0.01)

0.95(0.01)

0.97(0.06)

0.97(0.05)

−0.01(−0.03~0.01)

0.67

  1. Abbreviations: OSA, obstructive sleep apnea; EDS, excessive daytime sleepiness; BMI, body mass index; HOMA-IR, homeostasis model of assessment for insulin resistance index; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure