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Fig. 2 | Respiratory Research

Fig. 2

From: Intra-tracheal administration of a naked plasmid expressing stromal derived factor-1 improves lung structure in rodents with experimental bronchopulmonary dysplasia

Fig. 2

The effective pulmonary delivery of JVS-100. a Representative images of luciferase activity in the lungs of P5 and P14 rats who received PBS (control) and pLuc. b Increased SDF-1 protein expression in lung homogenates of P5 rats and (c) P14 rats who received IT JVS-100. SDF-1 expression was normalized to β-Actin. RA is room air and O2 is hyperoxia. P < 0.05; * RA-PL vs RA-JVS-100 or hyperoxia-PL; ** hyperoxia-PL vs hyperoxia-JVS-100; N = 4–5 animals /group. A representative western blot is shown in the lower panel.

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