Culture-Positive Pneumonia | Culture-Negative Pneumonia | Controls | |
---|---|---|---|
N | 9 | 5 | 8 |
Age, median [IQR], yrs | 58.3 [55.2, 62.6] | 55.8 [45.7, 62.8] | 61.2 [51.9, 67.4] |
Male, N (%) | 5 (55.6) | 2 (40.0) | 6 (75.0) |
BMI, median [IQR] | 24.0 [21.5, 34.6] | 31.2 [25.6, 32.9] | 28.1 [25.1, 36.1] |
SOFA Score, median [IQR]a | 6.0 [4.0, 6.0] | 7.0 [6.0, 7.0] | 5.0 [4.0, 8.0] |
PaO2:FIO2 ratio, median [IQR], mmHg | 158.0 [137.0, 275.0] | 150.0 [121.0, 208.0] | 221.5 [205.0, 319.5] |
Heart rate (median [IQR]), beats per minute | 107.0 [92.0, 117.0] | 83.0 [82.0, 88.0] | 81.5 [73.8, 85.5] |
SBP (median [IQR]) mmHg | 125.0 [102.0, 141.0] | 118.0 [117.0, 127.0] | 105.0 [97.8, 117.5] |
WBC, median [IQR], × 109 per liter (L) | 10.0 [7.4, 16.8] | 4.6 [3.5, 8.3] | 5.4 [4.5, 11.6] |
Platelets, median [IQR], × 109 per liter (L) | 190.0 [169.0, 281.0] | 155.0 [136.0, 210.0] | 141.0 [72.2, 171.0] |
Creatinine, median [IQR], mg/dL | 1.3 [1.1, 1.5] | 1.5 [1.5, 2.0] | 1.0 [0.8, 1.4] |
Respiratory Rate, median [IQR], 1/min | 22.0 [21.0, 24.0] | 21.0 [20.0, 24.0] | 17.0 [15.5, 17.2] |
PEEP, median [IQR], cm | 8.0 [5.0, 8.0] | 5.0 [5.0, 8.0] | 5.0 [5.0, 5.8] |
Tidal Volume (per kg of PBW), (median [IQR]), ml/kg | 6.8 [6.2, 8.4] | 6.2 [6.1, 6.6] | 6.3 [6.0, 7.1] |
Plateau Pressure, median [IQR], cm | 20.0 [13.0, 23.5] | 25.0 [21.0, 29.0] | 16.0 [13.0, 21.5] |
Type of mechanical breaths, n (%)b | |||
Volume control | 7 (77.8) | 4 (80.0) | 8 (100) |
Pressure control | 2 (22.2) | 1 (20.0) | 0 (0) |
Ventilator free days, median [IQR], days | 12.0 [0.0, 23.0] | 17.0 [6.0, 23.0] | 24.5 [24.0, 26.0] |
ICU Length of Stay, median [IQR], days | 8.0 [5.0, 18.0] | 11.0 [6.0, 12.0] | 4.5 [3.8, 5.0] |
Acute Kidney Injury, N (%) | 8 (88.9) | 4 (80.0) | 2 (25.0) |
30 Day Mortality, N (%) | 3 (33.3) | 1 (20.0) | 1 (12.5) |
On antibiotic therapy, N (%) | 9 (100) | 5 (100) | 5 (62.5) |
Antibiotic days, median [IQR], days | 12.0 [10.0, 24.0] | 21.0 [20.0, 24.0] | 3.5 [0.0, 7.5] |
CPIS, median [IQR], | 8.0 [7.0, 9.0] | 6.0 [5.0, 7.0] | 5.0 [4.0, 5.2] |
Procalcitonin, median [IQR], pg/μl | 2783.0 [1049.5, 4330.1] | 4866.0 [94.4, 4965.1] | 353.5 [250.4, 1531.6] |