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Table 2 Meta-analysis of 9 different expressed aging related genes in COPD group

From: Variable DNA methylation of aging-related genes is associated with male COPD

 Gene symbol

Effect size (SMD)

95% CI

p-value

 TGFB1

− 3.85

[−6.38, − 1.31]

0.003

 TP53

−2.66

[−4.44, − 0.88]

0.003

 MMP2

−1.76

[−2.96, −0.56]

0.004

 AREG

−3.02

[−5.25, −0.80]

0.008

 E2F1

−1.4

[−2.51, −0.30]

0.01

 HDAC1

−3.3

[−5.94, −0.67]

0.01

 NUF2

−2.62

[−4.72, −0.52]

0.01

 FOXO3

−1.84

[−3.34, −0.34]

0.02

 ATG3

−2.6

[−4.89, −0.30]

0.03

  1. A p value < 0.05 was considered statistically significant