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Table 3 CPET parameters before and after a single BPA session and multiple BPA sessions

From: Improved hemodynamics and cardiopulmonary function in patients with inoperable chronic thromboembolic pulmonary hypertension after balloon pulmonary angioplasty

Parameters

Single BPA session (n = 40)

Multiple BPA sessions (n = 10)

Pre-BPA

Post-BPA

P value

Before-first BPA

After-last BPA

P value

Peak WR, w

78.0 ± 40.6

86.7 ± 39.8

< 0.001

77.3 ± 47.6

96.2 ± 40.2

0.024

AT, ml/kg/min

10.7 ± 3.2

11.7 ± 3.1

0.098

10.3 ± 3.2

11.4 ± 3.3

0.57

Peak VO2, ml/kg/min

13.9 ± 3.7

15.2 ± 3.3

< 0.001

13.7 ± 4.5

16.1 ± 3.2

0.025

Peak VO2% predicted, %

54.5 ± 16.8

58.8 ± 15.3

< 0.001

53.7 ± 18.1

63.9 ± 14.1

0.015

Peak respiratory exchange ratio

1.01 ± 0.08

1.06 ± 0.10

< 0.001

1.04 ± 0.08

1.09 ± 0.10

0.046

VE/VCO2 slope

49.1 ± 15.3

45.3 ± 11.4

0.09

52.3 ± 16.7

44.0 ± 10.5

0.099

VE/VCO2 slope% predicted, %

181.4 ± 57.0

166.7 ± 40.6

0.079

191.4 ± 62.7

160.7 ± 37.8

0.098

OUES, ml/min/l/min

1250.5 ± 508.3

1329.1 ± 466.6

0.015

1205.0 ± 576.2

1341.0 ± 382.6

0.397

VEmax, l/min

47.2 ± 14.4

50.7 ± 15.1

0.027

52.4 ± 17.1

56.8 ± 15.4

0.197

VT@AT, l

1.19 ± 0.31

1.31 ± 0.34

0.035

1.20 ± 0.37

1.31 ± 0.33

0.422

VTmax, l

1.54 ± 0.38

1.67 ± 0.43

< 0.001

1.66 ± 0.39

1.80 ± 0.45

0.051

HR@AT, bpm

102.8 ± 18.3

108.1 ± 19.0

0.056

102.3 ± 15.1

108.6 ± 14.4

0.388

HRmax, bpm

128.9 ± 19.5

132.9 ± 16.0

0.16

126.4 ± 17.0

141.8 ± 13.0

< 0.001

HR% predicted, %

78.5 ± 10.5

84.9 ± 17.4

0.031

79.7 ± 9.8

88.7 ± 7.5

< 0.001

Peak VO2/HR, ml/bpm

7.52 ± 2.88

7.66 ± 2.55

0.381

7.24 ± 3.37

7.73 ± 2.49

0.466

Peak VO2/HR% predicted, %

69.0 ± 17.9

71.3 ± 15.3

0.068

66.6 ± 18.9

71.8 ± 12.0

0.272

Peak PetCO2, mmHg

24.7 ± 6.3

24.6 ± 7.0

0.916

22.4 ± 5.3

24.4 ± 4.9

0.39

Peak PetO2, mmHg

125.0 ± 5.0

125.7 ± 4.9

0.253

126.8 ± 3.8

127.8 ± 3.8

0.454

Peak VE/VO2

52.3 ± 12.6

51.6 ± 10.6

0.609

60.1 ± 14.4

54.4 ± 9.6

0.359

Peak VE/VCO2

51.8 ± 12.9

49.6 ± 10.7

0.078

57.9 ± 13.5

50.5 ± 10.5

0.19

Peak SpO2, %

91.0 ± 5.1

92.4 ± 4.7

0.484

89.1 ± 4.6

90.9 ± 4.1

0.213

  1. Peak WR peak work rate, AT anaerobic threshold, Peak VO2 peak oxygen consumption, VE/VCO2 minute ventilation/carbon dioxide production, OUES oxygen uptake efficiency slope, VEmax maximal minute ventilation, VT@AT tidal volume at the anaerobic threshold, VTmax maximum tidal volume, HR@AT heart rate at the anaerobic threshold, HRmax maximum heart rate, Peak VO2/HR peak oxygen consumption/peak heart rate, PetCO2 partial pressure of end-tidal carbon dioxide, PetO2 partial pressure of end-tidal oxygen, VE/VO2 minute ventilation/oxygen consumption, SpO2 pulse oxygen saturation
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Respiratory Research

ISSN: 1465-993X

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