Unique patterns of lower respiratory tract microbiota are associated with inflammation and hospital mortality in acute respiratory distress syndrome

Table 1 ARDS patient characteristics

	ARDS (N = 40)	Survivor (N = 24)	Non-survivor (N = 16)	p
Age (year)	67 (59–77)	67 (60–77)	67 (57–80)	0.62
Male gender	28 (70)	17 (71)	11 (69)	1.00
SOFA score at ICU admission	9 (7–11)	9 (7–11)	10 (7–12)	0.98
APACHE II at ICU admission	28 (22–34)	27 (22–35)	31 (23–34)	0.47
ARDS risk factor				0.11
Pneumonia	26 (65)	19 (79)	7 (44)
Sepsis	9 (23)	3 (13)	6 (38)
Aspiration	3 (8)	1 (4)	2 (13)
Other	1 (3)	1 (4)	0 (0)
Unknown	1 (3)	0 (0)	1 (6)
ARDS direct, (%)	28 (70)	18 (75)	10 (63)	0.49
Bacterial pneumonia, (%)	10 (25)	7 (29)	3 (19)	0.71
Prior antibiotic use, (%)	32 (80)	19 (79)	13 (81)	1.00
ICU stay, median	15 (7–24)	15 (7–22)	13 (4–28)	0.73
Mechanical ventilation days, median	10 (6–21)	10 (6–19)	9 (4–23)	0.65

Values are given as the median (interquartile range) or number (%). P-values were calculated using Fisher’s exact tests or Mann-Whitney U tests
SOFA Sequential Organ Failure Assessment, ICU Intensive Care Unit, APACHE Acute Physiology and Chronic Health Evaluation, ARDS Acute Respiratory Distress Syndrome

ISSN: 1465-993X