Fig. 9

Repeated lung function measurement in intubated C57BL/6 J mice. a, Study protocol. Lung function measurements were performed at day 0 and 19. n represents the number of surviving mice at a given time point. b, Average mice weight. c-k, Peak expiratory flow (“PEF”, c), Forced vital capacity (“FVC”, d), forced expired volume over 0.1 s (“FEV0.1”, e), FEV0.1/FVC ratio (f), newtonian resistance (“Rn”, g), tissue damping (“G”, h), tissue elastance (“H”, i), resistance (“Rrs”, j) and compliance (“Crs”, k) of the respiratory system in intubated mice at day 0 (“OTI 1”) and day 19 (“OTI 2”). Data represent individual mice and are analyzed by the Wilcoxon signed-rank test