Fig. 2
Effect of ST2 deficiency on ozone-induced airway hyperresponsiveness. Changes in pulmonary resistance (RL) induced by inhaled aerosolized methacholine were assessed in male (a) and female (b) wildtype (WT) and ST2 deficient (ST2−/−) mice exposed to air or ozone. Mice were either housed with other mice of the same genotype (same-housed) or with mice of the other genotype (cohoused). Data are expressed as mean ± SEM, *p < 0.05 vs Air, #p < 0.05 vs WT mice with the same exposure, $ p < 0.05 vs male mice. N = 6–11 per group for male mice and N = 5–8 per group for female mice