Fig. 2From: Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokersLoss of skin elasticity is associated with greater impairment in lung function and increased pulmonary emphysema. Skin elasticity was associated with pulmonary emphysema determined by %LAA and Hist15. Skin elasticity was not associated with impairment in FEV1, however a significant association was observed between quartiles of skin elasticity and the severity of airflow obstruction, diffusion impairment, lung hyperinflation (RV/TLC) and pulmonary emphysema. Legend: FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity in 1 s; DLCO, diffusion capacity for carbon monoxide; LAA% = low attenuation areas, lung voxels with Hounsfield Unit (HU) values less than −950; Perc15, HU value at the 15th percentile of the HU value histogram of lung voxelsBack to article page