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Table 3 Lung cancer incidence per 10,000 person-years by sex and age in patients with connective tissue disease-associated interstitial lung disease (CTD-ILD) and interstitial lung disease (ILD)-only

From: Lung Cancer development and mortality in interstitial lung disease with and without connective tissue diseases: a five-year Nationwide population-based study

Men

 

Women

 

Age (years)

Incidence CTD-ILD

Incidence ILD Only

RR

95% CI

P value

E value

Incidence CTD-ILD

Incidence ILD Only

RR

95% CI

P value

E value

40–49

161.7

48.8

3.23

1.11–9.39

0.03

5.91 (1.45-NA)

77.2

41.2

1.91

0.63–5.81

0.25

 

50–59

201.8

107.2

1.83

0.97–3.46

0.06

 

119.3

40.8

2.81

1.23–6.42

0.01

5.06 (1.76-NA)

60–69

294.2

286.4

1.02

0.67–1.54

0.90

 

152.2

83.1

1.78

0.99–3.18

0.05

 

70–79

352.3

288.8

1.20

0.75–1.93

0.43

 

170.6

129.1

1.31

0.74–2.32

0.35

 

≥ 80

414.3

424.9

1.00

0.36–2.77

0.99

 

114.4

318.0

0.43

0.10–1.78

0.24

 

Total

269.4

209.9

1.27

0.98–1.65

0.06

 

127.0

103.7

1.28

0.95–1.73

0.09

 
  1. RR Rate ratio, CI confidence interval, NA not available, E value was calculated by VanderWeele and Ding method [29]