Table 2 Characteristics of the tumor and surgical procedures in study participants according to PPC development (n = 488)
All (n = 488) | No PPCs (n = 436) | PPCs (n = 52) | p-value | |
|---|---|---|---|---|
Tumor histology | 0.003 | |||
Adenocarcinoma | 381 (78.1) | 350 (80.3) | 31 (59.6) | |
Squamous cell carcinoma | 81 (16.6) | 65 (14.9) | 16 (30.8) | |
Other NSCLCs | 26 (5.3) | 21 (4.8) | 5 (9.6) | |
Tumor location | 0.186 | |||
Right upper lobe | 164 (33.6) | 147 (33.7) | 17 (32.7) | |
Right middle lobe | 34 (7.0) | 31 (7.1) | 3 (5.8) | |
Right lower lobe | 99 (20.3) | 82 (18.8) | 17 (32.7) | |
Left upper lobe | 108 (22.1) | 100 (22.9) | 8 (15.4) | |
Left lower lobe | 83 (17.0) | 76 (17.4) | 7 (13.5) | |
Tumor staging | ||||
T stage | 0.296 | |||
cT1a | 120 (24.6) | 109 (25.0) | 11 (21.2) | |
cT1b | 136 (27.9) | 125 (28.7) | 11 (21.2) | |
cT2a | 163 (33.4) | 145 (33.3) | 18 (34.6) | |
cT2b | 39 (8.0) | 33 (7.6) | 6 (11.5) | |
cT3 | 30 (6.1) | 24 (5.5) | 6 (11.5) | |
N stage | 0.833 | |||
cN0 | 458 (93.9) | 409(93.8) | 49 (94.2) | |
cN1 | 30 (6.1) | 26(6.2) | 3 (5.8) | |
Extent of surgery | 0.005 | |||
Pneumonectomy & Bilobectomy | 18 (3.7) | 12 (2.8) | 6 (11.5) | |
Lobectomy | 370 (75.8) | 332 (76.1) | 38 (73.1) | |
Segmentectomy & Wedge resection | 100 (20.5) | 92 (21.1) | 8 (15.4) | |
VATS | 353 (72.3) | 321 (73.6) | 32 (61.5) | 0.093 |
MLND (%) | 0.992 | |||
None | 30 (6.1) | 27 (6.2) | 3 (5.8) | |
Selective | 38 (7.8) | 34 (7.8) | 4 (7.7) | |
Systematic | 420 (86.1) | 375 (86.0) | 45 (86.5) | |