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Fig. 5 | Respiratory Research

Fig. 5

From: Chronic obstructive pulmonary disease upper airway microbiota alpha diversity is associated with exacerbation phenotype: a case-control observational study

Fig. 5

Within-subject similarity is greater than between-subject similarity. Principal coordinate analysis using Bray-Curtis dissimilarity was plotted with color used to define each subject. Each subject’s oral wash (circle) and sputum (triangle) samples are connected by a colored, subject-specific line, which defines the within-subject oral wash-sputum similarity. Four subjects did not have sputum samples available or evaluable. Permutation testing demonstrated greater within-subject than between-subject similarity at these two sites (p < 0.001). Exacerbation phenotype was not significantly associated with changes in within-subject similarity (p = 0.95)

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