Fig. 5
From: Tobacco exposure inhibits SPLUNC1-dependent antimicrobial activity
Tobacco smoke reduces SPLUNC1’s ability to bind LPS. Graphs show Non-linear regression fit generated from one site specific binding of LPS derived from either H. influenzae (a) or P. aeruginosa (b) with 2 fold dilutions of SPLUNC1, cigarette and tobacco smoke exposed SPLUNC1 dissolved in Ringer’s solution to commercial cigarettes and several little cigars (all n = 9 per group). Statistically significant differences were measured using Kruskal-Wallis test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 different to Air + SPLUNC1