Fig. 3
From: Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia
Representative microscopy images for a) immunohistochemical 8-oxodG staining to detect oxidative DNA damage in pulmonary sections of hyperoxia and caffeine exposed rats. Quantitation of 8-oxodG cells counts in lung sections at b) P3 and with recovery on P15 (P3_P15) and P5 and with recovery on P15 (P5_P15), respectively. Data are expressed relative to the normoxia-exposed control group (100%) and the 100% values are 13.3 (P3), 7.0 (P3_P15), 6.2 (P5), and 7.6 (P5_P15) cells per mm− 2, respectively. Error bars represent SEM, n = 6–8/group. **p < 0.01 and ***p < 0.001 versus control (NO); ###p < 0.001 versus hyperoxia group (HY) with Mann Whitney test