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Fig. 7 | Respiratory Research

Fig. 7

From: Bradykinin sensitizes the cough reflex via a B2 receptor dependent activation of TRPV1 and TRPA1 channels through metabolites of cyclooxygenase and 12-lipoxygenase

Fig. 7

Effect of i.c.v. administered selective 15-LOX-1 inhibitor, ML-351 (ML) 5 μmole ml− 1 (n = 6) and 20 μmole ml− 1 (n = 6), versus vehicle (n = 5), on BK-enhanced citric acid-induced cough (a) changes in Penh (b) and Penh AUC (c). Values represent means + sem

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