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Table 3 Predicting factors for mortality in patients with tuberculous destroyed lung assessed by univariate cox analysis

From: Effect of tiotropium inhaler use on mortality in patients with tuberculous destroyed lung: based on linkage between hospital and nationwide health insurance claims data in South Korea

 

Hazard ratio

95% CI

p value

Age, years

1.053

1.040–1.066

<  0.001

Male sex compared to female

3.215

2.255–4.583

<  0.001

Body mass index

0.859

0.827–0.893

<  0.001

Ever-smoker

2.075

1.569–2.746

<  0.001

mMRC dyspnea scale

  

<  0.001

 0 (reference)

1.000

  

 1

1.497

1.074–2.085

0.017

 2

1.742

1.177–2.578

0.006

 3

3.139

2.127–4.633

<  0.001

 4

3.646

2.235–5.947

<  0.001

Charlson Comorbidity Index

1.234

1.180–1.290

<  0.001

Concomitant asthma

0.980

0.613–1.566

0.932

Concomitant COPD

1.738

1.049–1.784

0.021

ICS/LABA usage

0.849

0.582–1.238

0.394

FEV1, % predicted

0.981

0.975–0.987

<  0.001

FVC, % predicted

0.971

0.965–0.978

<.001

FEV1/FVC ratio, %

0.996

0.989–1.004

0.316

DLco, % predicted

0.963

0.953–0.973

<.001

X-ray severity (0 to 6)

1.618

1.471–1.780

<  0.001

Long-term oxygen therapy

2.036

1.380–3.004

<  0.001

  1. Abbreviations: mMRC modified Medical Research Council, COPD chronic obstructive pulmonary disease, LAMA long-acting muscarinic antagonist, ICS/LABA inhaled corticosteroid/long-acting beta-2 agonist, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, DLco diffusing capacity for carbon monoxide