Fig. 7

Photographs of a lung specimen in control lung tissues (a), interstitial inflammation and lymphoid infiltration in LPS (b and c), AG50 (d), AG100 (e) and AG150 (f) groups (magnification for each group; 10 × 20; scale bar; 2.5 mm). The degree of lung injury was measured using lung pathological score (g). ***;P < 0.001 compared to control group, +;P < 0.05, ++;P < 0.01 and +++;P < 0.001 compared to LPS group. Data are shown as mean ± SEM. The lung pathological changes were scored as follows: 1) no pathologic changes, 0; 2) patchy changes, 1; 3) local changes, 2; 4) scattered changes, 3 and 5) severe changes (in the most parts of the lung), 4. Statistical analysis were performed using one-way analysis of variance (ANOVA) followed by Tukey’s multiple comparison test