Variables | Study sample n = 52 | Patients with Vef and without DH | Patients with Vin and without DH | Patients with Vef and with DH | Patients with Vin and with DH | p value a |
---|---|---|---|---|---|---|
V’O2 at peak, ml/kg/min | 28.1 ± 8.2 | 31.0 ± 7.7 | 25.8 ± 7.3 | 30.7 ± 9.2 | 25.7 ± 7.9 | 0.180 |
Workload, watts | 121 [97; 169] | 168 [121; 216.5] | 109 [98; 146.5] | 127.5 [94.5; 188] | 102 [88; 138] | 0.067 |
Δ IC, L | − 0.19 [− 0.43; 0.15] | 0.24 [− 0.05; 0.37] | 0.16 [0.08; 0.55] | −0.43 [− 0.54; − 0.21] c e | −0.38 [− 0.43; − 0.26] c e | < 0.001 |
Δ VT, L | 0.89 [0.51; 1.33] | 1.34 [0.95; 1.61] | 0.92 [0.44; 1.24] | 0.88 [0.57; 1.19] b | 0.64 [0.29; 0.89] b | 0.039 |
RR at peak, breath/min | 37 [32; 44] | 34 [32.1; 41.5] | 31 [28; 38.9] | 38.8 [31.7; 42.5] | 44 [36; 51] | 0.073 |
V’E/V’CO2 at rest | 43.4 ± 5.9 | 39.8 ± 5.1 | 42.1 ± 5.0 | 43.4 ± 5.3 | 46.9 ± 6.2 b | 0.017 |
V’E/V’CO2 slope | 29.3 ± 4.8 | 25.6 ± 1.9 | 33.0 ± 4.4 c | 24.9 ± 2.7 e | 32.5 ± 2.3 c g | < 0.001 |
V’E/V’CO2 intercept, L∙min− 1 | 3.28 [1.95; 4.33] | 3.3 [2.5; 3.6] | 0.8 [0.2; 2.6] b | 4 [3.2; 7.4] b d | 3.6 [2.6; 5] d | 0.001 |
O2 pulse at rest, mL/beat/min | 3.2 [2.3; 3.9] | 3.3 [2.1; 4.5] | 3.3 [2.1; 3.9] | 3 [2.5; 3.9] | 3.3 [2.3; 3.9] | 0.948 |
Δ O2 pulse, mL/beat/min | 7.0 ± 2.6 | 8.8 ± 2.7 | 6.0 ± 2.1 b | 7.9 ± 3.0 | 5.9 ± 1.5 b | 0.008 |
Δ PETCO2 | 6 [4; 9] | 6.5 [4.7; 8] | 3 [0.5; 6] | 10 [6.7; 14] b e | 6 [3; 7] f | 0.001 |
HR recovery | 23 [15.2; 28] | 25 [21.7; 31] | 23 [15.5; 27.5] | 20.5 [14.2; 24.5] | 23 [13; 29] | 0.261 |
HR/VO2 | 56 [46; 65.7] | 47.5 [41.7; 59] | 59 [47.5; 74] | 50 [42; 64.2] | 62 [52; 73] | 0.122 |
DP reserve | 15,251.1 ± 4192.6 | 15,387.0 ± 5090.4 | 14,966.5 ± 3391.4 | 15,063.2 ± 4187.2 | 15,582.7 ± 4582.2 | 0.980 |
DP reserve/Workload | 123.8 ± 35.8 | 97.1 ± 36.1 | 129.9 ± 36.3 | 117.4 ± 27.9 | 142.3 ± 31.9 b | 0.011 |
SpO2 at rest, % | 96.7 ± 1.7 | 97.3 ± 1.9 | 97.5 ± 1.3 | 96.4 ± 1.8 | 95.9 ± 1.7 | 0.079 |
Δ SpO2, % | −2.0 ± 3.3 | −0.6 ± 2.5 | −1.1 ± 2.7 | −3.9 ± 3.8 | − 2.0 ± 3.4 | 0.065 |
Peak dyspnea | 0.51 [0.39; 0.77] | 0.43 [0.25; 0.62] | 0.55 [0.44; 0.73] | 0.52 [0.36; 0.88] | 0.57 [0.45; 0.95] | 0.384 |
Peak fatigue | 0.65 [0.45; 0.82] | 0.47 [0.38; 0.77] | 0.74 [0.60; 0.88] | 0.60 [0.34; 0.77] | 0.71 [0.57; 0.91] | 0.198 |