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Fig. 2 | Respiratory Research

Fig. 2

From: RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD

Fig. 2

Heatmap of differential gene expression correlation across all analyses. The row and column labels indicate the phenotype variable and the tissue. The results for each analysis were sorted by log2FoldChange and the Spearman correlation was calculated for each pair of results. The absolute value of these correlations is plotted in the heatmap. Clustering by euclidean distance is shown in the dendrograms. The region of correlation between the emphysema signature in blood and the smoking signature in the bronchial epithelium is outlined in the bottom black box (rows 12 & 13; columns 5–7). The region of correlation between the smoking and emphysema signatures in blood is outlined in the top black box (row 3; columns 5–7)

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