Table 3 Outcomes measured in the 7 RCTs
Study | Group | pCO2 levels* | △pCO2* | Intubation |
|---|---|---|---|---|
Bottino 2018 [20] | nHFOV | 46.6 (7.5) | − 3.4 (7.77) | 0/15 |
nCPAP | 49.9 (6.7) | 1.4 (7.31) | 0/15 | |
Klotz 2017 [16] | nHFOV | 54.8 (14.6) | 3.6 (12.66) | 0/13 |
nCPAP | 49 (8.1) | −1 (7.01) | 0/13 | |
Lou 2017 [21] | nHFOV | 35.1 (7.8) | −1.4 (7.85) | 5/34 |
nCPAP | 40.6 (7.8) | 2.4 (7.24) | 12/31 | |
Lou 2018 [22] | nHFOV | 41.5 (6.3) | −13 (7.43) | 9/33 |
BP-CPAP | 50.5 (6.5) | −3.1 (7.0) | 10/32 | |
Malakian 2018 [23] | nHFOV | 4/63 | ||
nCPAP | 9/61 | |||
Mukerji 2017 [24] | nHFOV | NA | NA | 6/16 |
BP-CPAP | NA | NA | 15/23 | |
Zhu 2017 [25] | nHFOV | NA | NA | 9/37 |
nCPAP | NA | NA | 22/39 | |
Zhu 2017 [26] | nHFOV | 43.7 (5.6) | −12.1 (5.08) | 4/17 |
nCPAP | 48 (4.7) | −6.3 (4.29) | 12/21 |