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Table 3 Outcomes measured in the 7 RCTs

From: Noninvasive high-frequency oscillatory ventilation as respiratory support in preterm infants: a meta-analysis of randomized controlled trials

Study Group pCO2 levels* pCO2* Intubation
Bottino 2018 [20] nHFOV 46.6 (7.5) − 3.4 (7.77) 0/15
nCPAP 49.9 (6.7) 1.4 (7.31) 0/15
Klotz 2017 [16] nHFOV 54.8 (14.6) 3.6 (12.66) 0/13
nCPAP 49 (8.1) −1 (7.01) 0/13
Lou 2017 [21] nHFOV 35.1 (7.8) −1.4 (7.85) 5/34
nCPAP 40.6 (7.8) 2.4 (7.24) 12/31
Lou 2018 [22] nHFOV 41.5 (6.3) −13 (7.43) 9/33
BP-CPAP 50.5 (6.5) −3.1 (7.0) 10/32
Malakian 2018 [23] nHFOV    4/63
nCPAP    9/61
Mukerji 2017 [24] nHFOV NA NA 6/16
BP-CPAP NA NA 15/23
Zhu 2017 [25] nHFOV NA NA 9/37
nCPAP NA NA 22/39
Zhu 2017 [26] nHFOV 43.7 (5.6) −12.1 (5.08) 4/17
nCPAP 48 (4.7) −6.3 (4.29) 12/21
  1. NA Not Applicated, * means ± SD, pCO2 levels refers to Post nHFOV or nCPAP/BP-CPAP