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Table 3 Unadjusted and adjusted correlation of ILD severity with body composition

From: Body composition, muscle function, and physical performance in fibrotic interstitial lung disease: a prospective cohort study

 

Unadjusted analysis

Adjusted for sex, age, weight

Men

Women

r

p-value

r

p-value

Coefficient (95% CI)

p-value

R2

SMI, kg/m2

 FVC, %-predicted

0.22

0.07

−0.06

0.71

0.012 (0.005 to 0.018)

0.0006

0.75

 DLCO, %-predicted

0.39

0.002

0.15

0.40

0.013 (0.006 to 0.021)

0.0009

0.76

 CPI

−0.40

0.002

−0.19

0.27

−0.016 (− 0.026 to − 0.007)

0.0001

0.76

 Dyspnea (UCSD SOBQ)

− 0.08

0.57

0.29

0.09

−0.004 (− 0.010 to 0.002)

0.19

0.74

Body fat, %

 FVC, %-predicted

−0.37

0.002

−0.30

0.04

−0.063 (− 0.105 to − 0.020)

0.004

0.70

 DLCO, %-predicted

0.03

0.79

0.12

0.51

0.001 (−0.050 to 0.052)

0.96

0.68

 CPI

0.05

0.68

−0.06

0.74

0.025 (−0.036 to 0.087)

0.42

0.69

 Dyspnea (UCSD SOBQ)

0.41

0.003

0.28

0.09

0.021 (−0.017 to 0.060)

0.28

0.70

  1. Coefficients are reported per one-unit change for the predictor variables. A positive coefficient indicates an increase in the outcome variable per unit of the predictor variable (e.g., SMI increases by an average of 0.012 kg/m2 for every 1% increase of FVC %-predicted)
  2. Abbreviations: CI confidence interval, CPI Composite Physiologic Index, C diffusion capacity of the lung for carbon monoxide, FVC forced vital capacity, r Pearson’s correlation coefficient, R2 coefficient of determination (variability in the outcome explained by the model), SMI skeletal muscle index, UCSD SOBQ University of California San Diego Shortness of Breath Questionnaire
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Respiratory Research

ISSN: 1465-993X

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