Table 3 Meta-analysis of the association between the alleles and genotypes of ADAM33 genetic polymorphisms and asthma risk in Chinese population
From: Association between ADAM33 polymorphisms and asthma risk: a systematic review and meta-analysis
SNPs | Comparison | N | Test of association | Test of heterogeneity | |||
|---|---|---|---|---|---|---|---|
OR (95%CI) | P | Ph | I2(%) | Model | |||
T + 1 (rs2280089, G/A) | A vs. G | 3 | 1.65 (0.73, 3.74) | 0.23 | < 0.0001 | 91 | R |
AA+AG vs. GG |  | 1.79 (0.70, 4.56) | 0.22 | < 0.0001 | 91 | R | |
T1 (rs2280091, A/G) | G vs. A | 15 | 1.36 (0.91, 2.02) | 0.13 | < 0.00001 | 91 | R |
GG + AG vs. AA |  | 1.45 (0.92, 2.27) | 0.11 | < 0.00001 | 90 | R | |
T2 (2,280,090, G/A) | A vs. G | 18 | 1.70 (1.33, 2.17) | < 0.0001 | < 0.00001 | 79 | R |
AA+AG vs. GG |  | 1.71 (1.33, 2.21) | < 0.0001 | < 0.00001 | 77 | R | |
Q1 (rs612709, G/A) | A vs. G | 4 | 1.45 (1.01, 2.07) | 0.04 | 0.02 | 68 | R |
AA+AG vs. GG | Â | 1.58 (1.02, 2.43) | 0.04 | 0.01 | 72 | R | |
S1 (rs3918396, G/A) | A vs. G | 5 | 1.00 (0.80, 1.25) | 0.99 | 0.33 | 14 | F |
AA+AG vs. GG | Â | 1.12 (0.70, 1.78) | 0.64 | 0.44 | 0 | F | |
S2 (rs528557, G/C) | C vs. G | 17 | 0.89 (0.76, 1.04) | 0.13 | < 0.00001 | 70 | R |
CC + GC vs. GG |  | 0.86 (0.66, 1.14) | 0.37 | < 0.0001 | 67 | R | |
F + 1 (rs511898, C/T) | T vs. C | 13 | 1.14 (1.04, 1.25) | 0.004 | 0.50 | 0 | F |
TT + TC vs. CC |  | 1.15 (1.02, 1.30) | 0.02 | 0.32 | 12 | F | |
ST + 4 (rs44707, C/A) | A vs.C | 5 | 0.96 (0.75, 1.23) | 0.75 | 0.01 | 69 | R |
AA+CA vs. CC | Â | 0.92 (0.68, 1.24) | 0.58 | 0.06 | 56 | R | |
ST + 5 (rs597980, C/T) | T vs. C | 3 | 0.86 (0.73, 1.02) | 0.08 | 0.79 | 0 | F |
TT + CT vs. CC |  | 0.83 (0.66, 1.04) | 0.11 | 0.76 | 0 | F | |
V4 (rs2787094, C/G) | G vs. C | 11 | 1.12 (0.73, 1.71) | 0.60 | < 0.00001 | 95 | R |
GG + CG vs. CC |  | 1.10 (0.63, 1.91) | 0.74 | < 0.00001 | 92 | R | |